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薄荷醇促渗透作用的研究进展
http://www.100md.com 《时珍国医国药》 2006年第9期
薄荷醇;,促渗透作用;,作用机理,,薄荷醇;,促渗透作用;,作用机理,1薄荷醇促进药物透过皮肤,2薄荷醇促进药物透过鼻腔粘膜,3薄荷醇促进药物透过胃肠粘膜,4薄荷醇促进药物透过口腔粘膜,5促渗透机理的研究,6展望,参考文献:
     摘要:对国内外近5年来薄荷醇在促进药物透过皮肤、鼻腔粘膜、胃肠和口腔粘膜以及其促渗透机理的研究作了综述,认为薄荷醇是一种很有价值的中药渗透促进剂,具有良好的应用前景,为进一步研究薄荷醇的促渗作用提供了依据。

    关键词:薄荷醇; 促渗透作用; 作用机理

    Advanced Research on Penetration Enhancing Effect of Menthol

    QI Hongyi, LI Li, WU Chunjie*

    (Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China; Beijing Qiyuan Yide Institute of Materia Medica, Beijing 100070,China)

    Abstract:In this paper, the effect of menthol on promoting drugs to penetrate skin, mucous membrane of nasal cavity, stomach intestine, and mouth and the mechanism of it's penetration enhancement are reviewed according to reports over the last 5 years in and out of China. This paper points out menthol which belongs to extractive of traditional Chinese medicine is a valuable penetration enhancer, has a fine perspective of application and provides a foundation for further investigation of penetration enhancing effect of menthol.

    Key words:Menthol; Penetration enhancing effect; Mechanism of action

    薄荷醇(menthol)又称薄荷脑,学名:5-甲基-2-异丙基-环己醇,是一种非常重要的环萜醇。天然来源主要是唇形科植物薄荷Mentha arvensis var.piperasceus 和欧薄荷Mentha piperita等挥发油中的主要成分 ......

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